Bile duct inflammation is referred to as Cholangitis. From your liver and gallbladder, your bile is carried into your small intestine by a network of tubes called the bile ducts (the duodenum). Bacterial infections are the primary cause of most occurrences of cholangitis. Even so, it may be a long-term problem (chronic). 

This clinical condition is characterized by fever, jaundice, and abdominal pain because of biliary tract sluggishness and biliary tract infection, respectively. An alternative term for it is “ascending cholangitis.” Cholangitis can range in severity from mild to life-threatening, even though Charcot said it was a serious and life-threatening infection at first. 

Symptoms 

Acute cholangitis (0.5 to 1.7 percent) can arise during therapeutic endoscopic retrograde cholangiopancreatography with the placement of a stent or postoperatively as a result of injury to the bile duct or a strictured biliary-enteric anastomosis (pancreaticoduodenectomy, liver transplantation, liver resection, and Roux-en-Y hepaticojejunostomy). Patients with a biliary-enteric anastomosis may have food, stones, or other debris obstructing the distal common bile duct (Sump syndrome). 

A stone in the gallbladder cystic duct can also induce acute cholangitis, as an extrinsic compression of the bile duct from the duodenal periampullary diverticulum (Mirizzi syndrome). Blood clots and parasite infections are examples of intrinsic causes of biliary blockage (mainly liver flukes and the roundworm Ascaris). In some cases, the center of a biliary stone can be a piece of worm stuck in the body. This can cause pyogenic cholangitis to happen over and over again. 

All three of these conditions are unusual causes of acute cholangitis blockage: chronic pancreatitis, duodenal periampullary diverticulum (Lemmel syndrome), and gallbladder stone impaction (Mirizzi syndrome). Two of the most prevalent causes of biliary obstruction are blood clots and parasite infections (mainly liver flukes and the roundworm Ascaris). Gallbladder stones can occur due to parasite remains remaining in the digestive tract. 

 

At Doral Health and Wellness, gastroenterology experts specialize in gut health and disease. Please call us at 347-868-1016. 

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